Status

From computation to validated biology.

Evolvia is converting a completed computational program into measured wet-lab data.

Computational discovery complete — 88-compound screen across PHD1/PHD2/PHD3/CP4H

Two lead branches designed; tool compound EBP-4 selected

Wet-lab proof-of-mechanism confirmed: p53-axis engagement (WB + qPCR)

EBP-4 suppresses MSS CRC proliferation, comparable to cisplatin at 48h (MTT)

Early endothelial tolerability signal (HUVEC IL-6)